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Gene testing for thalassemia
Gene testing for thalassemia

Gene testing for thalassemia

Brief introduction

  Thalassemia is one of the most common and harmful single-gene genetic diseases in the world, anemia or pathological state caused by the lack or deficiency of one or more globgenin strains in hemoglobin due to genetic begloper gene defects. Name and classify the type and degree of glober chain deficiency. According to the severity of the disease, divided into heavy, intermediate, light three types, heavy: 3-6 months after birth symptoms, often die in childhood;

    The disease is widely distributed in many parts of the world, black areas of the United States, Southeast Asia, the Indian subcontinent and southern China: Guangdong, Guangxi, Yunnan, Hainan and other places for high-risk areas, the population carrying rate of up to 24%. At least 350 million people worldwide carry the terrestrial poverty gene.


Yiligang Launches More Comprehensive Gene Testing Program
Missing α-thalassemia gene detection kit
4 types were tested at one time, and the Thai type with relatively high incidence in Guangxi District was tested to prevent leaks more comprehensively. Because China is a country with a large population flow, it is also necessary to test in other regions.
 
Non-deletion α-thalassemia gene detection kit
Detection of three types and missing alpha and beta thalassemias at one time forms the most comprehensive product on the market.
 
β-thalassemia gene mutation detection kit
Detecting 19 types at a time. Compared with other CFDA products, it exclusively tests -50M, which has a higher mutation frequency, to prevent leaks more comprehensively. Because China is a country with a large population flow, it is also necessary to test in other regions.
 
※ Each additional new genotype is the result of a large rheological data assessment. The mutation of each genotype is only a probability of occurrence for the general public, but for the occurrence, it is related to the happiness of the entire family! So we all take it seriously!
Product advantages

Comprehensive coverage: more comprehensive coverage of the incidence site detection, for each region to carry higher gene mutant type supplement, is currently a hot gene selection more comprehensive CFDA registered products, greatly reducing the risk of missed detection;
High accuracy: detection of known missing types of samples, the results show the corresponding missing type, accuracy is more than 99%;
High specificity: detection of non-poor human genome DNA samples, specifictocoming more than 99%;
Technology reliability: technology platform after many years of clinical and the vast number of hospitals recognized and verified;
Applicability:  The conditions of use are simple and can be carried out in a normal PCR laboratory. 

Product information and performance

Product name

Missing alpha-thalassemia gene test kit

Non-missing alpha-thalassemia 

gene testkit

Beta-thalassemia gene 

mutation test kit

Detection method

Gap-PCR Law

PCR-reverse point hybridization

Sample requirements

Anticoagulant whole blood or genomic DNA

Application instruments

Gene amplification instrument, electrophoresis

Gene amplification instrument, molecular hybridizer

Packaging specifications

25 tests/kit

High accuracy

Positive and negative compliance rates are up to 100%

High sensitivity

Stable detection of genomic DNA samples with a concentration of 2 ng/sL

Precision

In-batch and inter-batch products using standard genomic 

DNA testing for precision reference concentrations of 10ng/μL

Easy to operate 

time-saving

After amplification, you can produce results 

with simple electrophoresis

Both can be used for PCR, hybrid, 

color display at the same time

Repeatability

100% consistency

Genetic law
Suitable for the crowd

Causes of thalassemia;
Thalassaemia risk assessment of childcare before pregnancy;
Blocking of children with thalassaemia during pregnancy;
High-risk groups, newborn screening.